The Natural History Circuit presents a naturalist collection that was the basis for the Museum. It is distributed over 8 rooms where diversity, knowledge and the exotic, along with different fields of scientific knowledge, are exhibited, with special importance to zoology, geology, mineralogy and botany.

The exhibition is a tribute to the painter Domingos Rebêlo as a central figure in the Azorean artistic panorama of the 20th century. The exhibition presents pieces from different phases of the painter's creation over four decades, not only those with a regionalist nature, but also caricature, graphic arts, illustration and scenography.

This tour presents the architectural characteristics of past convent buildings, but also the diversity of spaces, their dynamics and purposes, as well as exploring the way of life of the Poor Clares belonging to the female branch of the Order of Friars Minor, founded by Saint Francis of Assisi.

The Sacred Art circuit focuses on the old College Church, where the lush façade, the resplendence of the altarpiece of the main altar, as well as the collection of 17th century tiles are assumed as a whole, in a unique monument of Baroque style. To this is added a gallery with a diversified collection where pieces from the 16th century stand out, as well as a valuable collection of works with a religious theme.

The long-term exhibition presents the life and artistic production of one of the greatest figures of Azorean and national sculpture in the first half of the 20th century. This exhibition is divided into thematic groups that expose his genesis, training, international acclaim, as well as his role in monuments design.